Skip to main content
. 2020 Apr 23;11(19):4969–4979. doi: 10.1039/d0sc00480d

Mechanical properties of global deformation in dsDNA and dsRNA calculated from all-atom MD simulation.

dsDNA dsRNA
This work Pulling MD57 Exp.63–75 This work Pulling MD57 Exp.72–76
Bend L p (nm) 39.17 ± 0.82 45–50 78.9 ± 3.4 60–100
Stretch η s (pN) 1435 ± 61 1280 ± 70 1450–1750 634 ± 15 480 ± 11 350, 500
Twist η t (pN nm2) 448 ± 16 303 ± 23 160–448 443 ± 14 310 ± 24 409
Twist-stretch coupling η ts −52.0 ± 9.0 −54.0 ± 3.0 −39 to −17 27.0 ± 1.0 34.0 ± 1.0 11.5