Table 1.

Features included in model development.

Demographics and clinical characteristics	Laboratory findings	Co-infection*
●Age at admission, years ●Gender ●Ever smoke (all life before IP) ● Comorbidity present (3 years before admission) ○ Cancer ○ Chronic Respiratory Disease ○ Cardiovascular Disease ○ Hypertension ○ Type 2 Diabetes ○ Respiratory Failure ○ Kidney Disease ○ Alzheimer’s Disease ○ Cirrhosis ● Symptoms* ○ Cough ○ Dyspnea ○ Tachypnea, respiratory rate > 20 ○ Hypoxemia, oxygen saturation ≤ 90% ○ Rhinorrhea ○ Nose congestion ○ Fever, temperature > 37C/98.6F ○ Sputum ○ Pharyngitis (sore throat) ○ Headache ○ Fatigue ○ Conjunctivitis ○ Diarrhea ○ Anosmia ○ Myalgias	●White blood cell count, K/uL ●Lymphocyte count, K/uL ●ALT, U/L ●Creatinine, mg/dL ●Lactate dehydrogenase, U/L ●Creatine kinase, U/L ●High-sensitivity cardiac troponin I, ng/mL ●D-dimer, ng/mL ●Prothrombin time, seconds ●Serum ferritin, ng/mL ●IL-6, pg/mL ●Procalcitonin, ng/mL ●Lactate dehydrogenase, U/L ●Platelet count, K/uL ●C-reactive protein, mg/dL ●Total bilirubin, mg/dL ●Blood urea nitrogen, mg/dL ●Albumin, g/dL ●O2 Saturation, mm/Hg ●Fraction of inspired oxygen, FiO2, % ●Aspartate Aminotransferase, U/L ●Sodium (Na+), mmol/L ●Potassium (K+), mmol/L	●Adenovirus ●Chlamydia pneumoniae ●Coronavirus ●Influenza A ●Influenza B ●Metapneumovirus ●Mycoplasma pneumonia ●Parainfluenza 1 ●Parainfluenza 2 ●Parainfluenza 3 ●Parainfluenza 4 ●Rhinovirus/Enterovirus ●Respiratory syncytial virus (RSV)

^*within 15 days before admission.