BLI experiments determined dissociation constant of synthetic compounds 1, 30 and 31 that bind to protein CCL-13, IL-8 and FGF-2. Inactive denotes a KD value greater than 400 μM.
Compound | K D (nm) | ||
---|---|---|---|
CCL-13 | IL-8 | FGF2 | |
1 | 498 | 28 | 5 |
30 | Inactive | 39 | 14.5 |
31 | 92 | 75 | 17 |