Aqueous self-assembly and drug encapsulation efficiency of bottlebrush copolymers.

Micelle	D h (nm)	PDI	Encapsulation efficiencya (%)
AB	93	0.08	—
ABC	113	0.05	—
CBA	120	0.07	—
ABC-stat	45	0.17	—
Dexamethasone/ABC	92	0.1	78
Ibuprofen/ABC	108	0.09	65
Ofloxacin/ABC	113	0.16	63
Paclitaxel (PTX)/ABC	104	0.14	91
Resiquimod (R848)/ABC	118	0.15	71

^aDrug encapsulation efficiency based on % of drug (5 mg) retained in ABC TBC (50 mg).