Substrate scope for the oxidative transformation of aryl alcohols to thioethersa.
![]() | |||||
---|---|---|---|---|---|
Substrates | Products | Yield | Substrates | Products | Yield |
![]() |
![]() |
97% |
![]() |
![]() |
79%* |
![]() |
![]() |
95% |
![]() |
![]() |
95% |
![]() |
![]() |
93% |
![]() |
![]() |
63% |
![]() |
![]() |
87% |
![]() |
![]() |
88% |
![]() |
![]() |
22% |
![]() |
![]() |
72%* |
![]() |
![]() |
32% |
![]() |
![]() |
86%* |
![]() |
![]() |
5%* |
![]() |
![]() |
80%* |
![]() |
![]() |
90%* |
![]() |
![]() |
89%* |
![]() |
![]() |
93%* |
![]() |
![]() |
87%* |
![]() |
![]() |
79%* |
![]() |
![]() |
69%* |
Experiments were performed on the 0.2 mmol scale unless otherwise noted. Optimized conditions: 0.2 mmol alcohols, 0.4 mmol diphenyldisulfane, 0.08 mmol CuSO4, 0.04 mmol phen, 0.8 mmol K2CO3, 200 mg 4 Å, 2 mL DMSO, 0.5 MPa O2, 140 °C, 12 h. *24 h. Yield was determined by GC.