Fig. 1. (A) Normalized fluorescence intensities of pTP-TFE, pFTAA and ThT in an Aβ aggregation assay starting with Aβ40 monomers (n = 3). (B–D) Representative TEM image of Aβ aggregates 90 min (B), 200 min (C) and 700 min (D) (white bar = 200 nm). (E and F) Fluorescence intensity based binding curve of pTP-TFE (E) and pFTAA (F) with Aβ aggregates collected at 90 min (red), 200 min (blue) and 24 hours (black) of the aggregation assay.
