Results of the transfer-hydrogenation of 2-phenylquinoline with catalysts 1a/b/c and 2a/b/c.
| ||||
|---|---|---|---|---|
| Catalysta | eeb [%] | v 0 [10−7 M s−1] | Catalysta | eeb [%] |
| (S,S)-1a | 81 | 3.7 | (S)-2a | −17 |
| (S,S)-1b | 84 | 3.1 | (S)-2b | −12 |
| (S,S)-1c | 82 | 2.0 | (S)-2c | −17 |
2.5 mol% catalyst, 5 mM quinoline.
Determined by chiral HPLC. Values given for the excess of (R)-6.