Table 3. – Predictive factors for cardiovascular risk. Univariate and multivariate analyses.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR [95% CI] | p-value | HR [95% CI] | p-value | |
| Age (1-year increment) | 1.036 [1.025; 1.047] | < 0.001 | 1.035 [1.024; 1.046] | < 0.001 |
| Sex (male) | 1.123 [0.900; 1.401] | 0.303 | - | - |
| History of CAD (yes) | 1.686 [1.329; 2.139] | < 0.001 | 1.324 [0.989; 1.772] | 0.059 |
| Previous AMI (yes) | 1.672 [1.338; 2.090] | < 0.001 | 1.515 [1.155; 1.988] | 0.003 |
| History of stroke/TIA (yes) | 1.738 [1.335; 2.263] | < 0.001 | 1.481 [1.132; 1.938] | 0.004 |
| History of PAD (yes) | 1.951 [1.520; 2.503] | < 0.001 | 1.651 [1.271; 2.143] | < 0.001 |
| DM (yes) | 1.191 [0.951; 1.492] | 0.127 | 1.227 [0.967; 1.557] | 0.093 |
| Hypertension (yes) | 0.829 [0.593; 1.159] | 0.272 | - | - |
| Diabetic nephropathy (yes) | 1.826 [1.324; 2.518] | < 0.001 | 1.438 [1.021; 2.025] | 0.037 |
| Smoker (yes) | 0.950 [0.656; 1.376] | 0.785 | - | - |
| Asymptomatic carotid artery disease (yes) | 1.008 [0.724; 1.404] | 0.963 | - | - |
| Combined drugs (yes)* | 1.083 [0.852; 1.377] | 0.513 | - | - |
Combined drugs: combined use of antiplatelet agent, statin, and angiotensin-converting enzyme inhibitor at baseline. AMI: acute myocardial infarction; CAD: coronary artery disease; HR: hazard ratio; PAD: peripheral artery disease; TIA: transient ischemic attack; DM: diabetes mellitus.