Table 2. – Baseline characteristics of patients from the included studies.
| Studies | Age, mean/median, years | Men, % | LVEF, mean/median, % | E/e' ratio | CAD, % | HTN, % | DM, % | ACE-I/ARB, % | β-blockers, % | MRA, % | Diuretics, % | Digoxin, % |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gargani 2015 | 70 | 73 | 37 | NA | NA | 57 | 39 | 63 | 60 | 60 | 100 | NA |
| Coiro 2015 | 72 | 68 | 38 | 19.11 ± 9.5 | 32 | NA | NA | NA | NA | NA | NA | NA |
| Gustafsson 2015 | 72 | 72 | NA | NA | 40 | 57 | 24 | 95 | 89 | 31 | 78 | NA |
| Cogliati 2016 | 81 | 42 | 48 | NA | 42 | 62 | 34 | 69 | 66 | 39 | 96 | 24 |
| Platz 2016 | NA | 61 | 32 | NA | NA | 71 | 49 | 67 | 89 | 29 | 92 | 21 |
| María 2016 | 79 | 54 | NA | NA | 33 | 94 | 54 | 72 | 57 | NA | 100 | 17 |
| Coiro 2016 | 73 | 55 | 39 | 16 ± 1 | 46 | NA | NA | NA | NA | NA | NA | NA |
| Miglioranza 2017 | 53 | 61 | 28 | 17 (13.30) | 30 | 53 | 23 | 66 | 95 | 53 | 62 | 50 |
| Pellicori 2018 | NA | 67 | NA | NA | 49 | 55 | 29 | 85 | 73 | 49 | 75 | NA |
LVEF: left ventricular ejection fraction; CAD: coronary artery disease; HTN: hypertension; DM: diabetes mellitus; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; MRA: mineralocorticoid receptor antagonist; NA: not applicable.