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Cortex Mori water extract (a) enhanced gut integrity and (b) decreased gut inflammatory protein ICAM-1 expression in db/db mice as detected by H&E staining and immunohistochemistry methods. DM, diabetic group; Met, metformin group; CM (L), CM (M), and CM (H) indicate diabetic mice administrated with low, medium, and high dose of Cortex Mori water extract. Representative pictures are shown (magnification: 200).
