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The inflammation and glycolysis in microglia were mediated by EZH2. (a, b) qRT-PCR and Western blot detected the knockdown efficiency of EZH2 in MG, respectively. ∗P < 0.05 vs. sh-NC group. (c) Western blot was performed to detect HIF-1α; inflammatory factors IL-6, TNF-α, and IL-17; and glycolysis-related gene PKM2, GLUT1, and HK2 expressions in the Control group, sh-NC group, and sh-EZH2 group. ∗P < 0.05 vs. Control group.
