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. 2021 May 28;37(6):108. doi: 10.1007/s11274-021-03070-x

Table 4.

Nanomaterials with photothermal activity as antibacterial agents

Nanomaterials Microbes Size (nm) Light wavelength (nm) Mechanisms of antibacterial activity References
AuNCs-DNase Gram positive and Gram-negative bacteria 808 Disrupt biofilm and kill gram positive and Gram-negative bacteria Xie et al. (2020)
Aniline nanogel and chitosan-containing AgNPs E. coli 78 405 The release of AgNPs causes Cell membrane damage Ballesteros et al. (2019)
AgNPs S. aureus, Pseudomonas aeruginosa 15–20 460

In vitro investigation showed a 10-log reduction in bacterial count in biofilm

In vivo study using mice showed a 100% reduction in 2 h. there was also a reduction in wound burden

Nour El Din et al. (2016)
[AL(OH)Pc(SO3Na)4] + Au–AgNPs + aBL Pseudomonas aeruginosa 14 660 There was a 3-log reduction Maliszewska et al (2018)
AgNPs + antibiotic + aBL S. aureus 15–20 460

There was a 100% reduction in bacterial growth within 8 h

Excellent synergistic activity

Akram et al. (2016)
Calixarene-NO donor conjugate E. coli, S. aureus 270 400 The release of No causes membrane damage Dahl et al. (1988)
PLGA NPs E. faecalis 665 There was a 96.7% reduction in growth within 10 min Gonzalez-Delgado et al. (2016)
CMP NPS B. subtilis, E. coli 1.2 W/cm2 For B. subtilis, there was a 97% reduction under 120 min while E. coli had a 95% reduction under 120 min Ma et al. (2016)
AuNWs E. coli, S. aureus 5 ± 1.5 808 Reduction of bacterial growth in vitro Liao et al. (2020)
Ti-GNRs surface E. coli, P. aeruginosa, S. epidermidis, S. aureus 49 ± 4 × 11 ± 2 808 Significant reduction in bacterial growth in vitro Yang et al. (2019)
TC-AuNSs S. aureus, P. aeruginosa Average diameter of 120 nm 808 Reduction in bacterial growth in vitro within 5 min of exposure to NIR laser irradiation Manivasagan et al. (2019)
PU-Au-PEG S. aureus, P. aeruginosa 40 × 10 808

Significant reduction in bacterial adhesion in vitro and in vivo

Effective photothermal killing reduction in biofilm formation

Zhao et al. (2020)