Table 1.
Anti-FCoV activities of the dipeptidyl and tripeptidyl derivatives.
| Dipeptidyl |
Tripeptidyl |
||||
|---|---|---|---|---|---|
| Compound | FCoV (EC50 μM) | CC50 (μM) | Compound | FCoV (EC50 μM) | CC50 (μM) |
| 18 | 0.02 ± 0.01 | >150 | 25 | 0.02 ± 0.01 | 70.29 ± 5.6 |
| 20 | 0.04 ± 0.04 | >150 | 26 | 0.86 ± 0.72 | 40.57 ± 10 |
| 21 | 0.10 ± 0.03 | >150 | 27 | 0.54 ± 0.28 | 32.34 ± 1.9 |
| 22 | 0.43 ± 0.31 | >150 | 28 | 0.04 ± 0.03 | 61.91 ± 0.2 |
| 23 | 0.06 ± 0.05 | >150 | 29 | 0.18 ± 0.12 | 32.01 ± 1.3 |
| 24 | 0.12 ± 0.05 | >150 | 30 | 0.06 ± 0.06 | 21.96 ± 5.1 |
| 31 | 0.06 ± 0.001 | >150 | |||
Measured as the mean and standard error of the means (SEM).