Table 6.
Summary of several studies that explored the prevalence of 2R/2R TYMS genotype.
| Author | Population | N | Prevalence N (%) |
|---|---|---|---|
| Zhu | Case and control infants (American Caucasians) | 78 and 132 | 16 (21) and 34 (26) |
| Zhu | Case and control infants (American Hispanics) | 144 and 396 | 25 (17) and 70 (18) |
| De Jonge | Children with ALL and matched control (Netherlands) | 244 and 491 | 51 (21) and 116 (24) |
| Gast | Children with ALL and matched control (Germany) | 457 and 541 | 95 (21) and 111 (21) |
| Lightfoot | Children with ALL and matched control (UK) | 759 and 754 | 193 (25) and 181(24) |
| Petra | Children with ALL and matched control (Slovenia) | 68 and 252 | 17 (25) and 76 (30) |
| Adleff | Colorectal (Hungary) | 102 | 18 (17.6) |
| Kristensen | Colorectal (Denmark) | 122 | 34 (28) |
| Vazquez | Healthy volunteers (Argentina) | 199 | 43 (26.1) |
| Canalle | Children with ALL and matched control (Brazil) | 126 and 300 | 33 (26) and 53 (18) |
| Silva | Children with ALL and matched control (Brazil) | 140 and 390 | 25 (18) and 66 (17) |
| Gallegos-Arreola | Colorectal and healthy subjects (Mexico) | 347 and 456 | 77 (22) and 85 (19) |
| Chan | Children with ALL and matched control (Indonesia) | 184 and 177 | 30 (16) and 0 (0) |
| Giovannetti | Children with ALL and matched control (Indonesia) | 71 and 44 | 1 (1) and 0 (0) |
| Yeoh | Children with ALL and matched control (Singapore) | 518 and 652 | 12 (2) and 15 (2) |
| Nazki | Children with ALL and matched control (India) | 43 and 144 | 8 (19) and 14 (10) |