Table 5.
Associations of season of birth with brain imaging markers, Rotterdam study, the Netherlands, 1990–2018
| Season of birth | Total brain volume | Gray matter volume | White matter volume | Hippocampus volume | ||||
|---|---|---|---|---|---|---|---|---|
| β | 95% CI | β | 95% CI | β | 95% CI | β | 95% CI | |
| Winter (Dec., Jan., Feb.) | − 0.09 | − 2.55, 2.38 | − 0.42 | − 3.21, 1.34 | 0.85 | − 1.80, 3.50 | − 0.01 | − 0.05, 0.02 |
| Spring (Mar., Apr., May.) | 0.51 | − 1.90, 2.92 | 0.69 | − 1.77, 2.69 | 0.05 | − 2.54, 2.65 | − 0.01 | − 0.04, 0.02 |
| Summer (Jun., Jul., Aug.) | Referent | Referent | Referent | Referent | ||||
| Fall (Sep., Oct., Nov.) | − 1.32 | − 3.78, 1.14 | 0.46 | − 1.41, 3.14 | − 2.18 | − 4.83, 0.47 | − 0.03 | − 0.06, 0.00 |
CI confidence interval
Differences in brain volumes (mL) with adjustment for age, sex and intracranial volume