Table 3.
Studies of bridging treatment (intravenous thrombolysis -IVT- plus endovascular treatment -EVT-) in acute ischemic stroke due to isolated cervical internal carotid artery occlusion
| Study | Treatment description | n | Definition of favorable outcome | Favorable outcome n (%) |
Mortality n (%) |
sICH n (%) |
Definition of successful recanalization | Successful recanalization, n (%) |
|---|---|---|---|---|---|---|---|---|
| Gliem 2017 | IVT + EVT | 12 | 90 days mRS ≤ 2 | 6 (50%) | 2 (16.7%) | 3 (25%) | "successful" according to carotid ultrasound | 11 (91.7%) |
| Paciaroni 2015 | IVT + EVT | 44 | 90 days mRS ≤ 2 | 20 (45.5%) | 9 (20.5%) | 11 (25%) | NA | NA |
| Widimsky 2017 | IVT + EVT | 6 | NA | NA | NA | NA | "successful" | 6 (100%) |
| Overall | 62 | 26 (46.4%) | 11 (19.6%) | 14 (25%) | 17 (94.4%) |
Legend. IVT, intravenous; EVT, endovascular treatment; mRS, modified Rankin scale; sICH, symptomatic intracerebral hemorrhage.