Table 1.
Demographics and clinical characteristics
| Characteristic | Pre-intervention (n = 77) | Post-intervention (n = 129) | p value |
|---|---|---|---|
| Age, yearsa | 63.7 ± 14.9 | 66 ± 14 | 0.28 |
| Female, n (%) | 42 (54.5) | 69 (53.5) | 0.88 |
| Race, n (%) | |||
| Caucasian | 55 (71.4) | 97 (75.2) | 0.55 |
| African–American | 13 (16.9) | 31 (24) | 0.23 |
| Other | 9 (11.7) | 1 (0.8) | < 0.001 |
| Severe immunodeficiency, n (%) | 24 (31.2) | 41 (31.8) | 0.93 |
| Source of bacteremia, n (%) | |||
| Genitourinary tract | 38 (49.4) | 71 (55) | 0.43 |
| Catheter related | 12 (15.6) | 8 (6.2) | 0.03 |
| Biliary tract | 5 (6.5) | 26 (20.2) | 0.008 |
| Intraabdominal | 11 (14.3) | 13 (10.1) | 0.36 |
| Skin and soft tissue | 1 (1.3) | 5 (3.9) | 0.41 |
| Respiratory tract | 2 (2.6) | 0 (0) | 0.14 |
| Other | 2 (2.6) | 2 (1.6) | 0.63 |
| Unknown | 6 (7.8) | 4 (3.1) | 0.18 |
| Pitt Bacteremia Scoreb | 1 (0, 2) | 2 (1, 3) | 0.33 |
| Organism, n (%) | |||
| E. coli | 27 (35.1) | 60 (46.5) | 0.11 |
| Non-E. coli EB | 34 (44.2) | 51 (39.5) | 0.52 |
| Klebsiella spp. | 16 (47.1) | 32 (62.7) | |
| Enterobacter spp. | 6 (17.6) | 8 (15.7) | |
| Citrobacter spp. | 3 (8.8) | 2 (3.9) | |
| Proteus spp. | 3 (8.8) | 7 (13.7) | |
| Morganella morganii | 1 (2.9) | 0 (0) | |
| Salmonella spp. | 1 (2.9) | 1 (2) | |
| Serratia marcescens | 4 (11.8) | 1 (2) | |
| Non-EB | 13 (16.9) | 13 (10.1) | 0.16 |
| Pseudomonas aeruginosa | 4 (30.8) | 9 (69.2) | |
| Pseudomonas putida | 0 (0) | 1 (7.7) | |
| Acinetobacter lwoffii | 2 (15.4) | 1 (7.7) | |
| Stenotrophomonas maltophilia | 3 (23.1) | 0 (0) | |
| Flavobacterium meningosepticum | 2 (15.4) | 0 (0) | |
| Vibrio fluvialis | 1 (7.7) | 0 (0) | |
| Alcaligenes xylosoxidans | 1 (7.7) | 0 (0) | |
| Moraxella osloensis | 0 (0) | 1 (7.7) | |
| Polymicrobial | 3 (3.9) | 5 (3.9) | 1 |
aMean ± standard deviation
bMedian (interquartile range)
EB Enterobacterales (isolated organisms include Klebsiella spp., Citrobacter spp., Enterobacter spp., Proteus spp., Morganella morganii, Salmonella spp., Serratia marcescens
Bold value indicates p values of < 0.05