Table 4.
Cancer characteristics and treatments, NLST
| PHC No. (%) |
No PHC No. (%) |
p-valuea | |
|---|---|---|---|
| Lung cancers diagnosed within 1-year of positive LDCT screening, No. | 40 | 510 | n/a |
| Histology, No. (%) | |||
| All non-small cell lung cancer (NSCLC) | 36 (90.0) | 462 (90.6) | 0.44 |
| Bronchioloalveolar carcinoma (BAC) | 2 (5.0) | 12 (2.4) | |
| Adenocarcinoma | 20 (50.0) | 260 (51.0) | |
| Squamous cell | 5 (12.5) | 119 (23.3) | |
| Large cell | 3 (7.5) | 30 (5.9) | |
| Other NSCLC | 6 (15.0) | 41 (8.0) | |
| Small cell lung cancer | 3 (7.5) | 38 (7.5) | |
| Carcinoid | 0 (0) | 6 (1.2) | |
| Unknown | 1 (2.5) | 4 (0.8) | |
| Lung Cancer Stage, No. (%) | |||
| Early | 25 (62.5) | 346 (67.8) | 0.43 |
| Late | 15 (37.5) | 153 (30.0) | |
| Not staged b | 0 (0) | 11 (2.2) | |
| Treatment by Stage | |||
| Early Stage, No. (%) | N=25 | N=346 | |
| Any surgery | 23 (92.0) | 329 (95.1) | 0.17 |
| Radiation only | 1 (4.0) | 2 (0.6) | |
| Radiation and chemotherapy | 0 (0) | 5 (1.5) | |
| Otherc | 1 (4.0) | 3 (0.9) | |
| None | 0 (0) | 7 (2.0) | |
| Late Stage, No. (%) | N=15 | N=153 | |
| Any surgery | 6 (40.0) | 53 (34.6) | 0.85 |
| Chemotherapy only | 3 (20.0) | 30 (19.6) | |
| Radiation and chemotherapy | 5 (33.3) | 50 (32.7) | |
| Otherd | 1 (6.7) | 8 (5.2) | |
| None | 0 (0) | 12 (7.8) |
a
Chi-square test statistic for differences by PHC status
b
Non-staged includes occult carcinoma, carcinoid, and those with missing or unavailable TNM
c
Other includes immunotherapy, radiofrequency ablation, brachytherapy, and all other treatments
d
In addition to ‘other’ this group includes those with radiation + chemotherapy + other and those with radiation only