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. Author manuscript; available in PMC: 2021 Sep 8.
Published in final edited form as: Nat Chem Biol. 2021 Mar 8;17(6):665–674. doi: 10.1038/s41589-021-00751-4

Extended Data Fig. 4. Bazedoxifene suppresses ferroptosis in mammalian cells.

Extended Data Fig. 4

a, Cell death quantified as the number of SYTOX Green positive (SG+) objects (i.e. dead cells) over time. Data are mean ± SD from two independent experiments. b,c, Cell death quantified by SG+ object counting. Data are from three or four independent experiments. d, Outline of the STY-BODIPY kinetic competition assay. Egg-phosphatidylcholine (1 mM) and STY-BODIPY (10 μM) are incubated with 0.2 mM di-tert-undecyl hyponitrite (DTUN), in addition to a radical trapping antioxidant (RTA-H).