. Author manuscript; available in PMC: 2022 Jun 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Apr 29;41(6):e369–e378. doi: 10.1161/ATVBAHA.121.316035

Table 4:

Stratified regression results for the association of sCD14 with heart failure and stroke events in the JHS

Outcome	Stratum	Events	N	HR	95% CI	p-value
Heart Failure	Female	144	1,732	1.32	(1.18,1.47)	<0.001
	Male	83	1,023	0.94	(0.79,1.11)	0.44
Stroke	<49.4 years	13	1051	1.45	(1.11,1.88)	0.006
	49.4-62.4 years	40	1009	1.14	(0.9,1.44)	0.29
	≥62.4 years	72	930	0.93	(0.78,1.12)	0.47

The relationship between sCD14 and heart failure was significantly modified by sex (p_interaction=0. 005); and between sCD14 and stroke by age (p_interaction<0.001). Hazard ratios (HR) and 95% confidence intervals (CIs) are reported per standard deviation increase in CD14 (316 ng/mL) by strata of sex or age (tertiles). P-values meeting the Bonferroni-corrected significance threshold of p≤0.006 are shown in bold.