Table 4.

Prevalence ratios and confidence intervals of the effect of time period on the comorbidity-index variables (1) severe CVD, (2) less severe CVD and (3) other vascular diseases, stratified by age and gender as estimated by means of logistic regression adjusting for within cluster variation. Adjusted for age (within each age group) and insurance duration.

			18–45 years n (men) = 19,340 n (women) = 20,022			46–64 years n (men) = 127,461 n (women) = 98,668			65 + years n (men) = 240,860 n (women) = 337,892
			PR	CI	p	PR	CI	p	PR	CI	p
CVD—less severe	Men	2005–2007	1	–		1	–		1	–
		2010–2012	1.15	1.11—1.18	< 0.001	1.08	1.07—1.09	< 0.001	1.06	1.05—1.06	< 0.001
		2015–2017	1.27	1.23—1.31	< 0.001	1.15	1.14—1.16	< 0.001	1.09	1.09—1.09	< 0.001
	Women	2005–2007	1	–		1	–		1	–
		2010–2012	1.12	1.08—1.16	< 0.001	1.06	1.06—1.07	< 0.001	1.04	1.04—1.05	< 0.001
		2015–2017	1.26	1.21—1.31	< 0.001	1.11	1.11—1.12	< 0.001	1.06	1.06—1.06	< 0.001
CVD—more severe	Men	2005–2007	1	–		1	–		1	–
		2010–2012	0.93	0.75—1.11	0.483	0.98	0.94—1.02	0.295	0.95	0.93—0.97	< 0.001
		2015–2017	1.02	0.82—1.22	0.840	0.92	0.88—0.96	< 0.001	0.84—0.88	< 0.001
	Women	2005–2007	1	–		1	–		1	–
		2010–2012	0.89	0.67—1.12	0.369	0.89	0.83—0.95	< 0.001	0.93	0.91—0.95	< 0.001
		2015–2017	0.64	0.46—0.82	< 0.05	0.79	0.74—0.85	< 0.001	0.81	0.79—0.83	< 0.001
Other vascular diseases	Men	2005–2007	1	–		1	–		1	–
		2010–2012	1.23	1.11—1.35	< 0.001	1.33	1.30—1.36	< 0.001	1.30	1.28—1.31	< 0.001
		2015–2017	1.48	1.34—1.63	< 0.001	1.62	1.58—1.66	< 0.001	1.65	1.63—1.67	< 0.001
	Women	2005–2007	1	–		1	–		1	–
		2010–2012	1.30	1.17—1.43	< 0.001	1.27	1.24—1.31	< 0.001	1.34	1.33—1.36	< 0.001
		2015–2017	1.49	1.34—1.63	< 0.001	1.59	1.54—1.63	< 0.001	1.76	1.74—1.78	< 0.001

CVD-less severe: hypertension, cardiac insufficiency or hyperlipidemia.

CVD-more severe: stroke, myocardial infarction or angina pectoris.

Other vascular diseases: retinopathy, nephropathy or polyneuropathy.