Table 1.
DETC antiparasitic activity, expressed in IC50 values ± standard deviation, against the different strains and forms of Trypanosoma cruzi after 24 h of exposure, based on results expressed by couting essay.
| Trypanosoma cruzi strains (DTUs) | IC50 epimastigote | IC50 trypomastigote | ||
|---|---|---|---|---|
| DETC (μM) | BZN (μM) | DETC (μM) | BZN (μM) | |
| Strain Dm28c (TcI) | 37.13 ± 7.58a | 78.12 ± 8.01a | 40.12 ± 6.58a | 91.95 ± 2.87b |
| Strain Y (TcII) | 50.41 ± 3.56b | 96.66 ± 5.38b | 31.19 ± 7.21b | 98.74 ± 3.98b |
| Strain QMM9 (TcIII) | 60.15 ± 6.45b | 101.38 ± 5.39b | 46.76 ± 5.11a | 103.47 ± 2.45c |
| Strain CL Brener (TcVI) | 49.12 ± 5.78b | 71.56 ± 7.98a | 43.83 ± 4.55a | 82.43 ± 5.83a |
The statistical analysis the Anova Test together with the Tukey Post-test. The statistical analysis used measure the IC50 value in each group under same conditions.
BZN benznidazole.