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. 2021 May 27;11:11180. doi: 10.1038/s41598-021-90509-8

Table 2.

Calculated whole lung dosimetry for the three age groups and particle sizes.

dp μm DepT % DepT×TVAFRC %-mL/cm2 DepT×TV×RR %-L/s DepTBSA %-L/s-m2 DepT×TVTVA % DepCAC %/cm2 DepRAR %/cm2
Infant 1 44.9 0.070 1.45 4.68 4.5 4.40E−2 77E−5
3 87.1 0.135 2.82 9.10 8.7 15.0E−2 55E−5
5 98.5 0.153 3.19 10.29 9.9 20.0E−2 7.6E−5
Child 1 28.5 0.022 1.91 2.48 12.0 0.35E−2 7.6E−5
3 72.5 0.055 4.85 6.26 30.5 1.10E−2 17E−5
5 88.1 0.067 5.89 7.65 37.0 2.60E−2 11E−5
Adult 1 22.6 0.017 2.83 1.73 22.6 0.11E−2 2.7E−5
3 65.6 0.051 8.20 5.01 65.6 0.39E−2 7.3E−5
5 82.9 0.064 10.36 6.32 82.9 0.88E−2 6.3E−5

dp particle diameter, DepT total deposition (inspiration and expiration together), total tissue dose (DepT×TVAFRC: where TV is the tidal volume and AFRC is the lung surface area at FRC, Table 1), rate of deposited particulate matter (DepT×TV×RR: where RR is the respiratory rate, Table 1), normalized by body surface area, BSA: DepT×TV×RRBSA, relative deposition percentages compared to the adult (DepT×TVTVA), conducting region tissue dose (DepCAC), and respiratory region tissue dose (DepRAR).