Figure 1.

Euler diagram illustrating the distribution and overlap between AKI diagnosis according to different AKI criteria. Numbers indicate the number of patients in that overlap zone, so who would be diagnosed by different criteria. SCrea: serum creatinine > 4.0 mg/dl or > 2 × baseline, where baseline = SCrea-1 whenever available, otherwise SCrea-2, or SCrea-3 (when neither SCrea-1 nor SCrea-2 are available) with Screa-1 defined as baseline Screa measurement as manually entered in ICIS by the treating physician at ICU admission; Screa-2 defined as the lowest pre-ICU measurement up to 365 days before ICU admission as extracted from the lab information system; Screa-3 defined as a back-calculated baseline Screa using the simplified 4-variable Modification of Diet in Renal Disease (MDRD) Study equation assuming an estimated glomerular filtration rate (eGFR) of 75 ml/min/1.73 m² for every patient³⁰; UO-1: total UO during the last 12-h period was ≤ 6 ml/kg; UO-2: total UO during each of the last 12 consecutive 1-h periods was ≤ 0.5 ml/kg.