Table 2.
Comorbidities prevalence and age-adjusted odds ratios among study patients at admission and comparison between disease groups.
| COVID-19* | Influenza | SARI | Others | Age-adjusted odds ratio (95%CI) | FDR-corrected p-value | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| (n = 398) | (n = 1,612) | (n = 2,292) | (n = 4,054) | (COVID-19 vs. influenza/SARI) | (odds ratio) | |||||
| Any comorbidity | 264 | (66.3%) | 1,316 | (81.6%) | 1,877 | (81.9%) | 2,766 | (68.2%) | 0.32 (0.24; 0.44) | 8.32E-12 | 
| Smoking | 35 | (8.8%) | 341 | (21.2%) | 458 | (20.0%) | 529 | (13.0%) | 0.32 (0.22; 0.48) | 2.05E-07 | 
| Cardiovascular disease | 207 | (52.0%) | 1,037 | (64.3%) | 1,420 | (62.0%) | 2,169 | (53.5%) | 0.46 (0.34; 0.61) | 9.26E-07 | 
| Any cancer | 38 | (9.5%) | 276 | (17.1%) | 536 | (23.4%) | 731 | (18.0%) | 0.4 (0.27; 0.58) | 1.11E-05 | 
| Chronic obstructive pulmonary disease (COPD) | 14 | (3.5%) | 166 | (10.3%) | 267 | (11.6%) | 185 | (4.6%) | 0.29 (0.16; 0.53) | 0.0002 | 
| Dementia | 40 | (10.1%) | 79 | (4.9%) | 188 | (8.2%) | 224 | (5.5%) | 2.82 (1.67; 4.76) | 0.0003 | 
| Solid cancer | 34 | (8.5%) | 234 | (14.5%) | 415 | (18.1%) | 631 | (15.6%) | 0.5 (0.33; 0.75) | 0.0019 | 
| Hematologic cancer | 4 | (1.0%) | 51 | (3.2%) | 140 | (6.1%) | 123 | (3.0%) | 0.19 (0.07; 0.53) | 0.0028 | 
| Hypertension | 166 | (41.7%) | 848 | (52.6%) | 1,091 | (47.6%) | 1,699 | (41.9%) | 0.66 (0.5; 0.87) | 0.0064 | 
| Ischemic heart disease | 57 | (14.3%) | 358 | (22.2%) | 452 | (19.7%) | 664 | (16.4%) | 0.69 (0.49; 0.97) | 0.0583 | 
| Asthma and bronchiectasis | 14 | (3.5%) | 114 | (7.1%) | 110 | (4.8%) | 114 | (2.8%) | 0.54 (0.28; 1.03) | 0.0963 | 
| Diabetes | 117 | (29.4%) | 542 | (33.6%) | 701 | (30.6%) | 1,031 | (25.4%) | 0.78 (0.59; 1.03) | 0.1159 | 
| Stroke | 30 | (7.5%) | 152 | (9.4%) | 244 | (10.6%) | 505 | (12.5%) | 0.7 (0.42; 1.16) | 0.2162 | 
| Hyperlipidemia | 146 | (36.7%) | 671 | (41.6%) | 868 | (37.9%) | 1,305 | (32.2%) | 0.87 (0.67; 1.14) | 0.3333 | 
| Osteoarthritis | 6 | (1.5%) | 27 | (1.7%) | 19 | (0.8%) | 77 | (1.9%) | 0.46 (0.1; 2.02) | 0.3333 | 
| Rheumatoid arthritis | 2 | (0.5%) | 29 | (1.8%) | 35 | (1.5%) | 41 | (1.0%) | 0.34 (0.04; 2.61) | 0.3333 | 
| Chronic kidney disease (CKD) | 51 | (12.8%) | 256 | (15.9%) | 281 | (12.3%) | 464 | (11.4%) | 0.92 (0.63; 1.34) | 0.6721 | 
Excluding mild severity cases.