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. 2021 May 14;12:661955. doi: 10.3389/fneur.2021.661955

Table 4.

Risk scores proposed for HT prediction with alteplase administration.

Score Name of score Components References
HTI – 0 to 6 points Hemorrhagic transformation index score ASPECTS (Alberta Stroke Program Early CT score), NIHSS, hyperdense middle cerebral artery sign, and presence of atrial fibrillation on ECG at admission (16)
GRASPS Glucose, Race, Age, Sex, Systolic blood Pressure, Severity Glucose at presentation, race [Asian], age, sex [male], systolic blood pressure at presentation, and severity of stroke at presentation [NIH Stroke Scale] (17)
HAT Hemorrhage after thrombolysis NIHSS score, hypodensity on CT scan (initial), serum glucose at baseline, and history of diabetes (18)
HeRS Hemorrhage Risk Stratification Age, infarct volume, eGFR (19)
HeRS plus Hemorrhage Risk Stratification Plus Addition of serum glucose, WBC count, and warfarin use on admission (19)
SITS-sICH Safe Implementation of Treatment in Stroke – Symptomatic IntraCerebral Hemorrhage risk NIHSS score, serum glucose, systolic blood pressure, age, body weight, stroke onset to treatment time, aspirin or combined aspirin and clopidogrel, and history of hypertension (20)
SEDAN Score Hemorrhage risk after thrombolysis Blood Sugar, Early infarct sign, Dense artery signs, Age, and NIHSS score (21)

NIHSS, National Institutes of Health Stroke Scale.