Table 8.

Leukocyte genes associated with HT in patients with ischemic stroke.

Gene	Function	Direction of expression
SMAD4	Codes for a member of the Smad family of signal transduction proteins, which are activated by TGF-β signaling to regulate the of target genes	Increased
INPP5D	Regulates proliferation and programming of myeloid cell	Increased
VEGI	Codes for a cytokine in the tumor necrosis factor ligand family	Decreased
AREG	Codes for a ligand for the epidermal growth factor receptor	Increased
MCFD2	Involved in the transport of coagulation factors V and VIII from the endoplasmic reticulum to the Golgi apparatus	Decreased
MARCH7	Regulates membrane receptor expression in several tissues, including leukocytes	Increased