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. 2021 May 14;13:647629. doi: 10.3389/fnagi.2021.647629

Table 2.

Critical appraisal of included studies using the AMSTAR-2 tool.

References Q1 Q2 Q3 Q4 Q5 Q6 Q7 Q8 Q9 Q10 Q11 Q12 Q13 Q14 Q15 Q16 Overall
quality
Peng et al. (2007) 1 1 0 1 1 1 1 0 1 0 1 1 1 1 1 1 M
Guo et al. (2008) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Lee et al. (2008) 1 0 0.5 1 1 1 0 1 1 0 1 1 0 1 0 1 CL
Zhu and Zhang (2009) 1 0 0 1 1 1 0 0 1 0 1 1 1 1 1 1 CL
Yuan and Zhang (2010) 1 0 0 0.5 1 1 0 1 1 0 1 1 1 1 1 0 CL
Liu et al. (2011) 1 0 0 1 0 0 0 1 1 0 1 1 1 1 1 0 CL
Tian et al. (2012) 1 0 0 1 1 1 0 1 1 0 1 1 1 0 1 1 CL
Cao et al. (2013) 1 0 0.5 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Fang et al. (2014) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Zhao et al. (2014) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 0 CL
Cao et al. (2014) 1 0 0 0.5 1 1 0 1 1 0 1 1 1 0 0 0 CL
Hu et al. (2014) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 0 CL
Zhou et al. (2015) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Liu et al. (2015) 1 0 0 0.5 1 1 0 1 1 0 1 0 0 1 0 1 CL
Mai and Zheng (2015) 1 0 1 0.5 0 0 0 1 1 0 1 0 0 1 1 0 CL
Lu et al. (2015) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Zhang et al. (2015) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Xu and Xie (2015) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Deng and Wang (2016) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Xiong et al. (2016) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Lin et al. (2016) 1 0 0 1 1 1 0 1 1 0 1 1 1 0 0 1 CL
Zou et al. (2016) 1 0 0 1 1 1 0 1 1 0 1 1 0 1 0 0 CL
Zhou et al. (2017) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Wan et al. (2017) 1 0 0.5 0.5 1 1 0 1 1 0 1 1 1 1 1 1 CL
Zhan et al. (2017) 1 0 0.5 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Lin et al. (2017) 1 0 0 1 1 1 0 1 1 0 1 1 0 0 0 1 CL
Kwon et al. (2018) 1 0 1 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Wu et al. (2018) 1 0 0 0.5 1 1 0 1 1 0 1 1 1 1 1 1 CL
Liu et al. (2018) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Li et al. (2018) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 0 CL
Kim et al. (2019) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Wang et al. (2019) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Li et al. (2020) 1 1 0 1 1 1 0 1 1 0 1 1 1 1 1 1 L
Wang et al. (2020) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Tang et al. (2020) 1 0 0 1 1 1 0 1 1 0 1 1 1 1 1 1 CL
Number of 1(%) 35 (100) 2 (6) 2 (6) 29 (83) 33 (94) 33 (94) 1 (3) 33 (94) 35 (100) 0(0) 35 (100) 33 (94) 30 (86) 31 (86) 29 (83) 27 (77)

1, Yes; 0.5, partial Yes; 0, No; M, Moderate; CL, Critically low; Q1–Q16, See Appendix E in Supplementary Material.