Table 1.

Participant timeline of TITAN SvS trial

Timepoints	Study period
	Enrolment	Postrandomisation
	0 month (initial visit)	3 months	4 months	1 year	2 years	3 years	4 years	5 years
Enrolment for all patients
Eligibility screen	X
Informed consent	X
Randomisation	X
Intervention: surgery group		X
Clinic follow-up
Surgery group			X	X	X	X	X	X
Surveillance group				X	X	X	X	X
Assessments
Demographics	X
Patient history	X
Weight/height	X		X	X	X	X	X	X
Vital signs	X		X
CBC, electrolytes, blood urea nitrogen, creatinine	X
HbA1c, random BG, cholesterol	X
ECG	X
Chest X-ray	X
CT chest
Surgery group	X			X
Surveillance group	X			X	X	X	X	X
QoL assessment	X			X		X
Stroke assessment			X	X	X	X	X	X
Acute aortic events assessment			X	X	X	X	X	X
Mortality assessment			X	X	X	X	X	X

BG, blood glucose; BUN, blood urea nitrogen; CBC, complete blood count; Cr, creatinine; QoL, quality of life.