Table 1.
Pathway analysis of differential metabolites of damaged cell models.
| Total | Expected | Hits | Raw p | Holm adjust | FDR | Impact | Pathway group | |
|---|---|---|---|---|---|---|---|---|
| Glycerophospholipid metabolism | 36 | 0.093 | 2 | 0.0030 | 0.257 | 0.257 | 0.199 | C versus U |
| Linoleic acid metabolism | 5 | 0.013 | 1 | 0.0128 | 1 | 0.540 | 0 | |
| alpha-Linolenic acid metabolism | 13 | 0.033 | 1 | 0.0331 | 1 | 0.744 | 0 | |
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | 14 | 0.036 | 1 | 0.0356 | 1 | 0.744 | 0.004 | |
| Pantothenate and CoA biosynthesis | 19 | 0.050 | 1 | 0.0482 | 1 | 0.744 | 0.007 | |
| Sphingolipid metabolism | 21 | 0.054 | 1 | 0.0531 | 1 | 0.744 | 0 | |
| Arachidonic acid metabolism | 36 | 0.093 | 1 | 0.0898 | 1 | 1 | 0 | |
| Sphingolipid metabolism | 21 | 0.108 | 3 | 0.0001 | 0.010 | 0.010 | 0.154 | C versus B |
| Glycerophospholipid metabolism | 36 | 0.186 | 3 | 0.0006 | 0.049 | 0.025 | 0.216 | |
| Linoleic acid metabolism | 5 | 0.026 | 1 | 0.0256 | 1 | 0.716 | 0 | |
| alpha-Linolenic acid metabolism | 13 | 0.067 | 1 | 0.0653 | 1 | 1 | 0 | |
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | 14 | 0.072 | 1 | 0.0702 | 1 | 1 | 0.004 | |
| Pantothenate and CoA biosynthesis | 19 | 0.098 | 1 | 0.0941 | 1 | 1 | 0.007 | |
| Glutathione metabolism | 28 | 0.144 | 1 | 0.1360 | 1 | 1 | 0.256 | |
| Arachidonic acid metabolism | 36 | 0.186 | 1 | 0.1717 | 1 | 1 | 0 | |
| Glycerophospholipid metabolism | 36 | 0.139 | 3 | 0.0002 | 0.018 | 0.018 | 0.216 | C versus D |
| Linoleic acid metabolism | 5 | 0.019 | 1 | 0.0192 | 1 | 0.808 | 0 | |
| alpha-Linolenic acid metabolism | 13 | 0.050 | 1 | 0.0494 | 1 | 1 | 0 | |
| Glycosylphosphatidylinositol (GPI)-anchor biosynthesis | 14 | 0.054 | 1 | 0.0531 | 1 | 1 | 0.004 | |
| Pantothenate and CoA biosynthesis | 19 | 0.074 | 1 | 0.0714 | 1 | 1 | 0.007 | |
| Sphingolipid metabolism | 21 | 0.081 | 1 | 0.0787 | 1 | 1 | 0 | |
| Glutathione metabolism | 28 | 0.108 | 1 | 0.1038 | 1 | 1 | 0.256 | |
| Arachidonic acid metabolism | 36 | 0.139 | 1 | 0.1317 | 1 | 1 | 0 |