Table 5.
Diagnostic performance of each parameter in distinction of different tissues.
| Parameter | AUC (95%CI) | Youden index | Sensitivity (%) | Specificity (%) | Threshold value | |
|---|---|---|---|---|---|---|
| TAA and ANHP | λHu | 0.987 (0.965–0.997) | 0.92 | 95.88 | 96.50 | 1.37 |
| NICAP (%) | 0.988 (0.967–0.997) | 0.91 | 96.39 | 94.41 | 6.55 | |
| NICPP (%) | 0.686 (0.628–0.741) | 0.27 | 68.04 | 58.74 | 40.15 | |
| ICD | 0.909 (0.868–0.940) | 0.67 | 71.54 | 95.10 | 0.70 | |
| AIF | 0.989 (0.968–0.998) | 0.93 | 96.91 | 95.80 | 0.47 | |
| TAA and TNA | λHu | 1.000 (0.978–1.000) | 0.98 | 99.48 | 98.25 | 0.85 |
| NICAP (%) | 0.997 (0.973–1.000) | 0.97 | 96.91 | 100.00 | 6.10 | |
| NICPP (%) | 0.962 (0.921–0.985) | 0.92 | 99.48 | 92.98 | 16.9 | |
| ICD | 0.717 (0.643–0.784) | 0.44 | 53.85 | 89.74 | 0.40 | |
| AIF | 0.688 (0.612–0.757) | 0.33 | 94.33 | 38.60 | 0.50 |
λHu, Slope of the spectral Hounsfield unit curve; NICAP, normalized iodine concentration at arterial phase; NICPP, normalized iodine concentration at portal venous phase; ICD, iodine concentration difference; AIF, arterial iodine fraction; TAA, tumor active area; ANHP, adjacent normal hepatic parenchyma; TNA, tumor necrotic areas.