Figure 5.

IL-1β production from PBMCs depleted of CD14+ monocytes in response to dmLT, ETVAX WCC and LPS. IL-1β concentrations in cultures with PBMCs and PBMCs depleted of CD14⁺ monocytes from adults (n = 4, closed symbols) and infants (n = 5, open symbols) stimulated with (A) dmLT (20 µg/ml), (B) ETVAX WCC (200,000 bacteria/ml) or (C) E. coli. O111:B4 LPS (10 ng/ml). Each symbol and line represent data from one participant. Statistical analysis was performed using the Wilcoxon matched-pairs signed rank test. ^** P < 0.01.