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. 2021 May 14;15:646678. doi: 10.3389/fnins.2021.646678

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Copyright © 2021 Gisabella, Babu, Valeri, Rexrode and Pantazopoulos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Perineuronal nets in the human and mouse hippocampus. (A) Photomicrograph of a representative perineuronal net labeled by wisteria floribunda agglutinin in the human hippocampus. Cells are counterstained with methyl green according to previously published methods (Pantazopoulos et al., 2010b). (B) Confocal image of a perineuronal net in the mouse hippocampus labeled with wisteria floribunda agglutinin (green), surrounding a parvalbumin positive neuron (red) co-expressing synapsin-1 (blue). Scale bars = 50 μm.