Summary of findings 8. Nonabsorbable tacks plus absorbable sutures compared to nonabsorbable tacks plus nonabsorbable sutures in primary ventral or incisional hernia repair.
| Nonabsorbable tacks plus absorbable sutures compared to nonabsorbable tacks plus nonabsorbable sutures in primary ventral or incisional hernia repair | ||||||
| Patient or population: People with primary ventral or incisional hernia repair Setting: Hospital Intervention: Nonabsorbable tacks plus absorbable sutures Comparison: Nonabsorbable tacks plus nonabsorbable sutures | ||||||
| Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | № of participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Risk with nonabsorbable tacks plus nonabsorbable sutures | Risk with nonabsorbable tacks plus absorbable sutures | |||||
| Recurrence (3 month) | 9 per 1000 | 27 per 1000 (1 to 644) | RR 3.00 (0.12 to 72.10) | 112 (1 RCT) | ⊕⊝⊝⊝ VERY LOWa | ‐ |
| Chronic pain (VAS 0 ‐ 100, 3 month) | The mean pain was 11.2 | MD 6.7 lower (12.9 lower to 0.5 lower) | ‐ | 112 (1 RCT) | ⊕⊕⊝⊝b LOW | ‐ |
| Health‐related quality of life | Not assessed in any study | |||||
| Seroma (3 month) | 0 per 1000 | 0 per 1000 (0 to 0) | RR 3.00 (0.12 to 72.10) | 112 (1 RCT) | ⊕⊝⊝⊝ VERY LOWa | ‐ |
| Haematoma (3 month) | 18 per 1000 | 54 per 1000 (6 to 499) | RR 3.00 (0.32 to 27.97) | 112 (1 RCT) | ⊕⊝⊝⊝ VERY LOWa | ‐ |
| *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; MD; mean difference | ||||||
| GRADE Working Group grades of evidence High quality: We are very confident that the true effect lies close to that of the estimate of the effect Moderate quality: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect | ||||||
aRated down by one level for risk of bias (performance bias) and by two levels for imprecision (effect estimate is based on very few events). bRated down by one level for risk of bias (performance bias) and by one level for imprecision (optimal information size threshold not reached).