Table I.
MWT | |||||
---|---|---|---|---|---|
Group | Baseline, g | 2 h | 4 h | 6 h | 8 h |
C | 12.10±3.47 | 12.78±3.44 | 12.00±3.31 | 12.11±2.22 | 12.14±2.73 |
IP | 12.10±3.47 | 2.03±0.97a | 0.97±0.77a | 1.73±1.13a | 8.05±3.59 |
NS | 12.78±3.44 | 1.92±1.09a | 0.63±0.35a | 2.31±0.63a | 5.55±1.96 |
CBX | 12.00±3.31 | 6.02±1.06b | 7.95±1.48b | 3.39±1.72 | 6.34±1.16 |
10panx | 10.39±3.59 | 7.00±1.63b | 5.94±1.73b | 2.43±0.93 | 7.95±1.58 |
Results are presented as the mean ± SD (n=6).
P<0.001 vs. C group
P<0.001 vs. IP group. MWT, mechanical withdrawal threshold; C, control group; IP, incision pain; NS, normal saline; CBX, carbenoxolone; 10panx, pannexin-1 mimetic inhibitory peptide.