Table II.
TWL | |||||
---|---|---|---|---|---|
Group | Baseline, g | 2 h | 4 h | 6 h | 8 h |
C | 25.13±0.69 | 24.73±0.81 | 25.01±0.98 | 25.14±0.53 | 24.64±0.68 |
IP | 25.13±0.69 | 5.54±1.15a | 3.32±0.36a | 5.98±0.55a | 9.17±1.99a |
NS | 24.73±0.81 | 6.07±0.58a | 3.32±0.57a | 6.39±1.32a | 9.12±0.46a |
CBX | 25.27±0.69 | 13.76±3.33b | 17.08±2.73b | 13.53±3.73b | 18.74±0.90 |
10panx | 24.68±0.65 | 18.57±2.64b,c | 15.82±2.42b | 13.77±2.70b | 20.96±2.06c |
Results are presented as the mean ± SD (n=6).
P<0.001 vs. C group
P<0.001 vs. IP group
P<0.05 vs. CBX group. TWL, thermal withdrawal latency; C, control group; IP, incision pain; NS, normal saline; CBX, carbenoxolone; 10panx, pannexin-1 mimetic inhibitory peptide.