Fig. 27.

Histopathologically proven splenic hemangiomatosis in two patients. a 42-year-old female patient with no significant past medical history presented to ER with fever and malaise. Axial plane postcontrast abdominal CT image demonstrated multiple nodular hypodense lesions in the spleen (arrows). Infectious etiologies were considered, and a US-guided percutaneous biopsy was performed. Histopathological examination confirmed splenic hemangiomatosis. b 34-year-old female patient presented with left upper quadrant pain. Axial plane T2W-fat-suppressed abdominal MR image showed multiple hyperintense nodular lesions (arrows) almost completely replacing the splenic parenchyma. Splenectomy was performed, and histopathological examination confirmed splenic hemangiomatosis