Table 4.
Performance of optimal platelet cut-offs in validation cohort
|
Platelet cut-off (× 109/L)
|
AUROC
|
Sensitivity (%)
|
Specificity (%)
|
Positive predictive value (%)
|
Negative predictive value (%)
|
Entire validation cohort | 143 | 0.85 (0.76-0.93) | 79 | 84 | 33 | 98 |
HBV | 143 | 0.81 (0.53-1.00) | 83 | 82 | 29 | 98 |
HCV | 143 | 0.83 (0.72-0.94) | 75 | 86 | 31 | 98 |
HDV | 143 | 0.87 (0.74-1.00) | 100 | 60 | 47 | 100 |
Table 4 displays the calculated cut-offs and sensitivity, specificity, positive predictive values, and negative predictive values for each the calculated optimal cut-off within the validation cohort. AUROC: Area Under the Receiver Operating Characteristics curve. HBV: Hepatitis B virus; HCV: Hepatitis C virus; HDV: Hepatitis D virus.