Table 3.
Activity Score | Alleles (Examples) | Type of Allele and Genotype |
---|---|---|
>2.25 | *1/*1 × N, *1/*2 × N b*2 a/*2 × N b, *1 × 2/*9 | Increased activity, Ultra rapid metabolizer |
≤2.25 to ≥1.25 | *1/*10, *1/*41, *1/*9, *1/*1, *1/*2, *2 × 2/*10 | Wild-type, Normal metabolizer |
>0 to <1.25 | *4/*10, *4/*41, *10/*10, *10/*41, *41/*41, *1/*5 | Reduced function, Intermediate metabolizer |
0 | *3/*4,*4/*4,*5/*5,*5/*6 | Non-functional, Poor metabolizer |