Table 6.
Activity Score CYP2D6 | Genetic Phenotype | Weak Inhibitor and Moderate Inhibitor | Strong Inhibitor |
---|---|---|---|
0 | PM | Activity score × 0.5 = PM | Activity score × 0 = PM |
> 0 < 1.25 | IM | Activity score × 0.5 = IM | Activity score × 0 = PM |
> 1.25 < 2.25 | NM | Activity score × 0.5 = IM | Activity score × 0 = PM |
>2.25 | UM | Activity score × 0.5 = NM | Activity score × 0 = PM |