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. 2021 May 20;14(5):487. doi: 10.3390/ph14050487

Table 6.

Phenoconversion in CYP2D6, and the calculation of the activity scores and the resulting phenotype.

Activity Score CYP2D6 Genetic Phenotype Weak Inhibitor and Moderate Inhibitor Strong Inhibitor
0 PM Activity score × 0.5 = PM Activity score × 0 = PM
> 0 < 1.25 IM Activity score × 0.5 = IM Activity score × 0 = PM
> 1.25 < 2.25 NM Activity score × 0.5 = IM Activity score × 0 = PM
>2.25 UM Activity score × 0.5 = NM Activity score × 0 = PM