Table 1.
mRNA expression of CTAs in tumor and TFL of HCC-patients. 1 Percentage of hepatocellular carcinomas (HCC) expressing mRNA of the CTA–meaning a Ct-value <35 and relative expression >0.001 (n = 100); 2 Mean relative expression (relative to the geometric mean of the 3 household genes- GUSB, HPRT1, PMM1) level in HCCs expressing the CTA and range; 3 Mean relative expression of the CTA in HCC expressing the CTA, relative to the relative mean expression in 3 testis tissues; 4 Percentage of paired tumor-free liver (TFL) tissues expressing mRNA of the CTA (n = 100); 5 Mean relative expression level in TFLs expressing the CTA and range; 6 Mean relative expression of the CTA in TFL expressing the CTA, relative to the relative mean expression in 3 testis tissues; 7 Percentage of non-cancerous/non-dysplastic cirrhotic liver tissues expressing the CTA (n = 35); * % in male.
CTA | mRNA-Positive HCC (%) 1 | Mean in mRNA-+ HCC (Range) 2 | Relative Expression HCC (Compared to Testis) 3 | mRNA-Positive TFL (%) 4 | Mean in mRNA-+ TFL (Range) 5 | Relative Expression TFL(Compared to Testis) 6 | mRNA-Positive Cirrhotic Tissue 7 |
---|---|---|---|---|---|---|---|
CAGE1 | 14.4 | 0.082 (0.003–0.711) |
0.188 | 2.0 | 0.009 (0.003–0.015) |
0.020 | 0 |
CT47A1 | 26.8 | 1.311 (0.001–20.565) |
0.632 | 6.1 | 0.255 (0.01–0.769) |
0.123 | 0 |
MAGEA1 | 58.6 | 0.403 (0.003–1.926) |
4.170 | 13.0 | 0.055 (0.005–0.188) |
0.567 | 0 |
MAGEA9 | 14.1 | 0.41 (0.001–4.953) |
2.848 | 1.0 | 0.035 (0.035–0.035) |
0.243 | 0 |
MAGEA10 | 12.4 | 0.123 (0.002–0.518) |
1.080 | 4.1 | 0.028 (0.004–0.088) |
0.249 | 0 |
MAGEB2 | 24.2 | 0.395 (0.002–2.4) |
0.761 | 6.0 | 0.053 (0.018–0.127) |
0.102 | 0 |
MAGEC1 | 47.5 | 0.109 (0.001–0.841) |
0.407 | 32.0 | 0.047 (0.002–0.466) |
0.174 | 28.6 |
MAGEC2 | 55.6 | 0.692 (0.001–9.305) |
1.542 | 19.0 | 0.041 (0.003–0.28) |
0.091 | 25.7 |
NYESO1 | 10.1 | 0.13 (0.007–1.04) |
0.525 | 1.0 | 0.018 (0.018–0.018) |
0.071 | 0 |
PAGE1 | 18.2 | 0.37 (0.002–2.225) |
1.001 | 5.0 | 0.059 (0.009–0.179) |
0.159 | 2.9 |
SLCO6A1 | 25.8 | 0.095 (0.002–0.411) |
0.053 | 4.1 | 0.011 (0.004–0.017) |
0.006 | 2.9 |
TSPY * | 21.0 | 0.827 (0.004–7.401) |
34.135 | 4.8 | 0.218 (0.001–0.641) |
9.012 | 4.2 |