Figure 7.

Pretreatment with either Mito-DC protects kidneys from ischemia reperfusion injury in allogeneic transfer studies. Mice were intravenously (i.v.) injected with 0.5 × 10⁶ DCs (Veh-DC or Mito-DC) one day before bilateral kidney IRI. (A) Protocol for experimental setup. (B) Plasma creatinine (C,D) Quantification of acute tubular injury (ATN) and renal histology (H&E). Scale bar (whole kidney section), 1000 µm and box inset, 200 µm. * p ≤ 0.05, student t test. Data represent means ± SEM, Unpaired t-test.