AD	Alzheimer’s disease
Aβ	amyloid β
mTOR	mechanistic target of rapamycin kinase
SGLT2	sodium glucose cotransporter 2
APP/PS1 mice	double transgenic mouse model of Alzheimer’s disease over expressing amyloid precursor protein, encoding the Swedish mutations at amino acids 595/596 and an exon-9-deleted human PS1
Tg2576 mice	transgenic mouse model, which express a 695-aa residue splice form of human amyloid precursor protein modified by the Swedish Familial AD double mutation K670N-M671L
3xTg-AD mice	triple-transgenic mouse model harboring PS1M146V, APPSwe, and tauP301L transgenes
ATP	adenosine triphosphate
MAPT	microtubule associated protein tau
ROS	reactive oxygen species
IDE	insulin-degrading enzymes
APP	amyloid precursor protein
TZDs	thiazolidinediones
GLP1	glucagon-like peptide-1
DPP-4	dipeptidyl peptidase-4
IGF-1	insulin-like growth factor-1
PS1	presenilin 1
PS 2	presenilin 2
APOE	Apolipoprotein E
PPARs	peroxisome proliferator-activated receptors
AChE	acetylcholinesterase
AMPK	adenosine 5′mmonophosphate-activated protein kinase
PPARs	peroxisome proliferator-activated receptors
PI3K	phosphatidylinositol-3-OH kinase
IRS-2	insulin receptor-2
NLRP3	nod-like receptor pyrin domain containing 3