Figure 6.

Fluorescence Meta II Decay: The t_1/2 for the retinal decrease that closely parallels de Meta II decay process under our experimental conditions was determined from experimental results depicted in Figure 4. The t_1/2 values for immunopurified ROS, WT, and I307N mutant, with (dark blue) and without VPA treatment (grey), are reported. The mean value and standard error (SE) were obtained from independent purifications (n = 3). Treatment with VPA does not cause a significant effect on the active conformation stability of WT Rho (*) but a statistically significant decrease in the stability of the Meta II conformation of the I307N mutant (**) (p < 0.05).