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. 2021 May 20;26(10):3044. doi: 10.3390/molecules26103044

Figure 13.

Figure 13

(a) Effect of RNLE treatment (25–50 µg/mL) on IL-6 secretion in HaCaT cells stimulated with a combination of histamine and TNF-α (100 µM + 25 ng/mL, 24 h); the amount of IL-6 in the stimulated condition was 64.50 ± 25.85 pg/mL. (b) Effect of RNLE treatment (25–50 µg/mL) on IL-6 secretion in HaCaT cells stimulated with histamine (100 µM, 24 h); the amount of IL-6 in the stimulated condition was 3.20 ± 1.10 pg/mL. Cetirizine 0.1 µM was used as the reference compound; ** p < 0.01, *** p < 0.001 vs. stimulus.