Table 1.

The spectrum of nonalcoholic fatty liver disease (NAFLD).

Condition	Features
Nonalcoholic fatty liver (NAFL)	Simple steatosis No evidence of inflammation, necrosis, and fibrosis
Nonalcoholic steatohepatitis (NASH)	Steatosis associated with pericellular fibrosis, lobular inflammation, and apoptosis. Histological findings are indistinguishable from alcoholic steatohepatitis [57]. NASH affects 3% to 6% of the U.S. population with a risk of progression to cirrhosis in about 20% of the cases [58,59,60,61] Possible progression to hepatocellular carcinoma (HCC) [62]
Cryptogenic cirrhosis	Late stage of progressive hepatic fibrosis and steatotic chronic liver disease Distortion of the architecture of the liver and growth of regenerative nodules May progress to HCC
Hepatocellular carcinoma (HCC)	Primary tumor of the liver that usually develops in the setting of chronic liver disease