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. 2021 May 19;22(10):5351. doi: 10.3390/ijms22105351

Figure 2.

Figure 2

Mechanisms of action of metformin and cellular outcomes. Proteins affected by metformin, either via AMPK-dependent and AMPK-independent pathways, are indicated. In red are outcomes that are inhibited by metformin. In blue are those that are enhanced by metformin.