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. 2021 May 19;11(5):327. doi: 10.3390/metabo11050327

Figure 9.

Figure 9

Volcano plots of the significant metabolites from central carbon metabolism (A) and untargeted metabolites (B) using a fold change (FC) threshold of ≥ 1.5 or ≤ 0.66 and a p-value of ≤0.05. For a full list of significant metabolites, see Supplementary Information, Tables S2 and S3. The red circles are the significant metabolites that were upregulated in the ferrets infected with the SA01 isolate relative to the VIC01 isolate. The green circles are the metabolites that were downregulated in the SAC01 isolate relative to the VIC01 isolate.