Table 4.

Enteral feeding interventions improving survival in experimental animal models of NEC.

Fat-based interventions	PUFA [45] MFGM [48]
Carbohydrate/sugar-based interventions	HMO [42,49,88] Hyaluronan 35 kD [94]
Protein/amino acid-based interventions	Lactadherin [51] Lysozyme [131] rPAF-AH [52]
Hormone/growth factor/vitamin-based interventions	HB-EGF [41,58,59,62,105]
Probiotic interventions	Bacteroides fragilis ZY-312 [113] Lactobacillus reuteri DSM 17938 [68,69,132] Lactobacillus reuteri ATCC PTA 4659 [68] Lactobacillus reuteri biofilm on sucrose loaded microspheres [72] Lactobacillus reuteri biofilm on maltose loaded microspheres [72] Bifidobacterium adolescentis [76] Bifidobacterium infantis [75] Bifidobacterium breve M-16V [117]
Other interventions	Surfactant protein A [80] Human β-defensin-3 [81]

PUFA, polyunsaturated fatty acids; MFGM, milk fat globule membrane; HMO, human milk oligosaccharides; rPAF-AH, recombinant platelet-activating factor acetylhydrolase; HB-EGF, hemoglobin-binding EGF-like growth factor.