Table 2.

Frequencies of alleles and genotypes (%) for polymorphisms of RAAS genes in studied groups.

Gene Polymorphisms	Genotypes and Alleles	Control (n = 62)	CAD (n = 113)	Restenosis (n = 54)	without Restenosis (n = 59)	Restenosis
						under 65 Years (n = 36)	over 65 Years (n = 18)	before 12 Months (n = 22)	after 12 Months (n = 32)
AGT rs699	TT	31	42	53 *	33	58	44	55	53
	TC	48	36	30 *	42	25	39	32	28
	CC	21	22	17 *	25	17	17	13	19
	T C	55 45	60 40	68 32	54 46	70.5 29.5	63.5 36.5	71 29	67 33
AGT rs4762	TT	14	22	24	20	25	22	14	31 *
	TC	30	15	9	20	8	11	14	6 *
	CC	56	63	67	60	67	67	72	63
	T C	29 71	29.5 70.5	28.5 71.5	30 70	29 71	27.5 72.5	21 79	34 66
AGTR1 rs5186	AA	53	52	47	58	50	39	41 *	50
	AC	27	33	33	32	30	39	50 *	22
	CC	20	15	20	10	20	22	9	28
	A C	66.5 33.5	68.5 31.5	63.5 36.5	74 26	65 35	58.5 41.5	66 34	61 39
AGTR2 rs1403543	A	45	60 **	63	57	71	47	70	56
	G	55	40	37	43	29	53	30	44
REN rs2368564	GG	60	53	39 *	66	44	28 *	36	41
	AG	32	30	37 *	24	36	38 *	36	38
	AA	8	17	24 *	10	20	34 *	28	21
	G A	76 24	68 32	57.5 * 42.5 *	78 22	62 38	47 * 53 *	54 46	60 40
REN rs41317140	CC	45	62 **	56	68	58	50	50	59
	CT	55	32 **	37	29	34	44	50	28 *
	TT	0	6 **	7	3	8	6	0	13 *
	C T	72.5 27.5	78 22	74.5 25.5	82.5 17.5	75 25	72 28	75 25	73 27
CYP11B2 rs1799998	CC	26	26	20	30	22	17	23	19 *
	CT	43	52	60	46	58	61	41	72 *
	TT	31	22	20	24	20	22	36	9 *
	C T	47.5 52.5	52 48	50 50	53 47	51 49	47.5 52.5	43.5 56.5	55 45
ACE rs4646994	II	24	26	26	25	19	39	32	22
	ID	61	45 **	39	51	44	28	32	44
	DD	15	29 **	35	24	37	33	36	34
	I D	54.5 45.5	48.5 51.5	45.5 54.5	50.5 49.5	41 59	53 47	48 52	44 56

Note: *—significantly different from the group of patients without restenosis, **—significantly different from the control group (p < 0.05).